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There is now persuasive evidence that consumption of folic acid supplements by women immediately prior to conception and in the rst 12 weeks of the pregnancy greatly reduces the risk of the baby developing a neural tube defect The term neural tube defect covers several developmental defects in which the brain, spinal cord, skull and/or vertebral column fail to develop normally In some cases, there is almost complete failure of brain and skull development (anencephaly) and these babies die before or shortly after birth Spina bi da is a failure of the spinal canal to close and so the spinal cord bulges out of the back Children born with spina bi da suffer from a range of physical disabilities such as paralysis and incontinence, and may have neurological damage caused by hydrocephalus.

Figure 29-4: The new process places the content in a database where server-side scripts can retrieve it as necessary.

About 1 in 250 UK pregnancies are affected by these conditions and about 1 in 4000 babies is born with a neural tube defect; many affected fetuses are detected by prenatal screening and aborted Studies dating back to the 1960s have suggested a link between folate insuf ciency and the occurrence of neural tube defects (see DoH 1992 for details and references to these early studies) MRC (1991) report the results of a double blind trial using over 2000 women with a previously affected pregnancy that was set up speci cally to test whether large periconceptual doses of folic acid reduced the recurrence rate of this condition Women with a previous history of an affected pregnancy are ten times more likely to have another affected pregnancy than the general female population.

In any case, the Web server must know how to handle server-side script requests calling a CGI page (for example, validate.cgi) via any method will only cause an error in the server unless it knows how to process the request. In the case of most server-side scripts, the Web server simply turns over processing of the script to an interpreter or the operating system. The script is executed in a separate environment, able to draw upon other resources but still have its output sent to the HTTP client.

Half of these women took 4 mg/day folic acid when they were planning to conceive and in the rst three months after conception There was a 72% lower recurrence in women taking folic acid than in those who did not take it; other supplemental vitamins had no measurable effect Subsequent studies (eg Czeizel and Dudas 1992) have shown that lower doses of folic acid reduce rst occurrence in women with no previous history of an affected pregnancy It is not thought that folate insuf ciency per se is a major cause of these conditions but rather that some women have a genetically determined variation in the enzyme methionine synthase which reduces its.

(4.84)

//just a code fragment, not part of RegDemo wsprintf( (LPTSTR)&bBuffer,TEXT( %s Data:%x%x%x ), TEXT( REG_BINARY ), *bData, *bData[1], *bData[2] );

Each time you open a new page, whether in the existing window or in a new window, Dreamweaver temporarily names the file Untitled-n, where n is the next number in sequence. This prevents you from accidentally overwriting a new file opened in the same session.

The primary goal of human and material resource planning is the ef cient and effective allocation of resources to a project. The fundamental problem that resource planners must deal with is resource scarcity; the need for resources usually outstrips their availability. In view of that reality, planners must carefully match available resources with project tasks. In matrix organizations, where many projects are

(iii) a temperature-dependent phase change The high temperatures beneath ocean ridge crests might cause a transition to a mineralogy of lower density Suppose the average temperature to a depth of 100 km below the Moho is 500 C greater at the ridge crest than beneath the anking regions, the average density to this depth is 33 Mg m 3 and the volume coef cient of thermal expansion is 3 10 5 per degree In this case the average mantle density to a depth of 100 km would be 005 Mg m 3 less than that of the anking ocean basins If isostatic equilibrium were attained, this low-density region would support a ridge elevated 22 km above the anking areas If the degree of partial melting were 1%, the consequent decrease in density would be about 0006 Mg m 3.

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